Surgical Management of Total Colonic Aganglionosis

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Total Colonic Aganglionosis in Siblings

Hirschsprung’s disease (HD) is attributed to failure of craniocaudal neural crest cell migration in the hindgut. Histopathology is absent of ganglion cells in the myenteric and submucosal plexuses. Most patients present with intestinal obstruction, in which delayed meconium passage is the most important history when suspecting HD. In eighty percent of cases, the pathology is limited limited to ...

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Ten-year experience in the management of total colonic aganglionosis.

PURPOSE The aim of this study was to review the 10 years' experience in the management of patients with total colonic aganglionosis (TCA) and follow-up of their health condition. METHODS Cases of 25 patients with TCA in the Children's Hospital of Fudan University from 1996 to 2005 were reviewed and analyzed. The confirmed diagnosis was established by an intraoperative frozen-section biopsy of...

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Total colonic aganglionosis in Hirschsprung disease.

Total colonic aganglionosis (TCA) is a relatively uncommon form of Hirschsprung disease (HSCR), occurring in approximately 2%-13% of cases. It can probably be classified as TCA (defined as aganglionosis extending from the anus to at least the ileocecal valve, but not >50 cm proximal to the ileocecal valve) and total colonic and small bowel aganglionosis, which may involve a very long segment of...

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Surgical outcomes of total colonic aganglionosis in children: a 26-year experience in a single institute.

BACKGROUND There is a lack of consensus regarding the treatment of total colonic aganglionosis (TCA) with respect to perioperative morbidity, mortality, complications, and functional outcomes. The aim of this study was to review the results of surgical TCA treatment over a 26-year period and characterize the outcomes. METHODS We retrospectively reviewed the clinical characteristics, surgical ...

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Comprehensive review of procedures for total colonic aganglionosis.

PURPOSE A variety of procedures have been described for the treatment of total colonic aganglionosis (TCA); however, there is no consensus as to a superior operative method. The objective of this review is to evaluate the operative methods used to treat TCA and their effectiveness with respect to morbidity, mortality, rates of enterocolitis, and functional outcomes. METHODS We searched Medlin...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1972

ISSN: 0003-4932

DOI: 10.1097/00000658-197209000-00010